The area is thought to have been occupied by the Baraparapa people long before white settlement and prehistoric burials of world importance were found locally in 1925 and in the late 1960s.
Major Thomas Mitchell passed through the area on his 1836 exploration of 'Australia Felix'. The first settlers came to the district from the north in 1835 or 1836. However, the boon of irrigation did not get under way until just before the First World War. The myxomatosis virus made its first successful debut in local rabbit warrens c.1950.
Unbeknownst to most Australians Cohuna's casein factory became involved in one of the most famous projects in human history when its produce became a part of the diet of the astronauts flying the Apollo space missions.