"I'm a zombie the first four or five days I travel," said Chris Baiz of Los Angeles. "Tried everything. I wake up at 1 or 2 am and then lie there awake."
"After returning to LA from a New York trip, sleeping through the night and awakening the next day, I found myself bonking around the house like a misguided pinball wizard, dopey and loopy," said Kathryn Rueby of Torrance.
In the case of one recent traveller, jet lag can put you in a mental haze that can lead to agonising disruptions.
"After arriving in Ireland, I fell asleep every two to three hours in the van," recalled Jory Schulman of Los Angeles. "I left my backpack at the dry cleaners in Kinsale. Luckily, it was left untouched, as my passport was inside."
What's the answer? Medical professionals and avid long-distance travellers recommend heavy hydration and advocate quickly adopting the meal times and sleep patterns of your destination.
"Rule No. 1: Stay on local time," said Dr. Robert Winters of Santa Monica, who deals with long-distance travellers as medical director of Westside Travel and Immunisations Inc. "(Experts) say to minimise alcohol, but one drink can help you relax.
"Eye shades and earplugs are key while flying," he added.
Instead of watching movies or reading on planes, Winters favours sleeping, particularly on overnight flights. "I might take an Ambien or melatonin. I don't do both."
Winters recommended 3 to 5 milligrams of melatonin, an over-the-counter supplement that triggers sleep.
When it comes to waking up, sleep experts at the Mayo Clinic recommend light therapy - either natural sunlight or a lamp - when you're travelling east. Conversely, experts there urge westbound travellers to draw the blinds in a time zone where the sun is staying up longer than you are accustomed.
Body clocks are tricky timepieces, and tough to reset quickly, experts said. During jet lag, cells in two parts of the brain fall out of sync. The health journal Medical News Today said the older the traveller, the worse the symptoms and the longer it takes to recover.
Among veteran travellers, conventional wisdom is that every time zone crossed requires a day of recovery. So a nine-hour time change on a trip from Rome would require nine days to rebound once you return home.
The issue is significant enough that aircraft makers are adjusting cabin pressures to help offset symptoms. For instance, Boeing's 787 is now pressurised at 6,000 feet, 2,000 feet lower than most other aircraft. Altitude chamber tests show that the body absorbs more oxygen into the blood this way, and passengers experience fewer headaches and less fatigue.
Although there is no sure cure for jet lag, prevention can make a difference in the severity of symptoms. Frequent fliers cite the benefits of lots and lots of water.
"I drink water the minute I get off the plane," said Mary Garripoli of LA "For the first 24 hours, just water, no iced tea, no wine. When I come home, it's the same thing."
"I was a flight attendant for many years," said Patricia Dotzler of Los Angeles. "I found that drinking a lot of water starting three days before departure, plus during and after flights ... then taking a good walk after arriving at the hotel helped a lot."
Like Winters, travel blogger Suzanne Stavert recommended adjusting to local schedules when you get to your destination.
"The absolute best way to get over jet lag is to get on local time immediately," Stavert said. "Do not nap. Stay hydrated, and go to sleep around 9 pm the first night of the trip and wake up at a normal local time. It has worked for me travelling to any time zone all over the world."
"My dad, who worked in travel for 40 years, gave me one tip: Plan to get in to your destination in the afternoon and force yourself to stay up until a relatively normal early bedtime in the country where you're staying," said financial journalist Kathy Kristof of La Canada Flintridge.
And more sleep tips from a parent on the front lines:
"Don't let your already grumpy teens sleep all day when you get to Europe; make them adjust," said Joshua Kreinberg of Pasadena, who vacationed in France with his family in early August. "They are going to be grumpy anyway because they are teens on a family vacation."